The SOLSTICE trial enrolled 406 participants across nine countries, randomly assigning them to treatment groups
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All cancer cell types tested were more sensitive to apoptosis upon depletion or inhibition of Rlip compared with any nonmalignant cell types of ectodermal, endodermal, or mesodermal lineages, indicating that the function of Rlip was more important for cancer cells than normal cells
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Researchers found that those who started GLP-1 drugs were 10% less likely to visit the emergency department and 14% less likely to be hospitalized over the following year, compared to those starting topiramate - a standard preventive migraine medication